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26 IGF-1 plays a primary role in articular cartilage, where it balances the synthesis of type II collagen and proteoglycans for chondrocyte regulation

2 Mitochondrial dysfunction and DN The development of DN is closely associated with damage to mtDNA, mitochondrial respiratory chain disorders, mitochondrial dynamics disorders, mitophagy damage, and elevated mitochondrial derivative ROS with the development of oxidative stress

(PubMed) Zimmermann MB, Galetti V

Grupos en los que puede ser ms relevante La relevancia de la carnitina puede aumentar cuando hay ingesta diettica baja (por ejemplo, dietas estrictamente vegetales) o en situaciones clnicas que alteran la homeostasis (p